Estrogen Metabolism Blood Test
Estrogen is a critical hormone that influences various aspects of your health, including reproductive function, bone strength, and cardiovascular well-being. Estrogen metabolism refers to how your body processes and breaks down estrogen into different metabolites. These metabolites can have different effects on your health, with some being more protective and others potentially more harmful.

Understanding your estrogen metabolism can help with the following:
- Identify Hormonal Imbalances: Effective metabolism of estrogen helps maintain balanced hormone levels, which can reduce symptoms like mood swings, fatigue, breast pain, menstrual cramps and weight fluctuations.
- Understand Your Cancer Risk: Certain estrogen metabolites are linked to a higher risk of hormone-sensitive cancers, such as breast and endometrial cancer.
- Assess Your Detoxification Capacity: The ability of your liver to effectively process and excrete estrogen metabolites (through Phase I and Phase II detoxification) reflects your overall detoxification capacity, indicating how well your body can handle and eliminate not just estrogen but other toxins and hormones as well.
A blood sample is analyzed to measure the levels of various estrogen metabolites. This includes assessing key metabolic pathways, such as:
- 2-Hydroxylation: Often associated with protective effects against cancer.
- 4-Hydroxylation and 16α-Hydroxylation: Pathways that can produce metabolites linked to increased cancer risk.
- Methylation: A detoxification process that helps your body safely eliminate estrogen metabolites.
Based on your results, we can:
- Personalize Your Care Plan: Tailor your diet, lifestyle, and supplementation to support healthy estrogen metabolism and overall detoxification.
- Assess Cancer Risk: Identify potential risks and implement proactive strategies to reduce your risk of hormone-sensitive cancers.